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11 Lateral ventricular administration of GLP-1 or exendin-4 in mice reduced endogenous levels of amyloid beta-protein (a protein that promotes Alzheimers disease), and infusion of GLP-1 and exendin-4 into rat hippocampal neurons also prevented cell death induced by amyloid-beta protein
The small sample requirements of CE-based methods make them attractive for preclinical studies involving limited tissue availability, such as microdissected brain regions or small biopsy specimens from animal models
sin embargo, es fundamental conocer sus posibles efectos secundarios y ser precavido
doi: 10.1111/j.1530-0277.2006.00002.x
These interesting results provide a very big hint for the study of the pharmacological mechanism of drugs against altitude hypoxia
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