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Both are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Clinical trials indicate that the medication is safe for extended use, with most patients experiencing mild to moderate gastrointestinal side effects such as nausea, vomiting, diarrhea, or constipation

Before GLP based therapy became available, losing 10 to 20 percent of body weight through medication alone was extremely rare

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These data provide preliminary evidence that GLP-1RAs could act through peripheral mechanisms to suppress alcohol intake, the authors wrote in their paper, published Wednesday in Scientific Reports

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