Limit Processed Foods, Sugar, and Alcohol Highly processed foods, added sugars, and alcohol can disrupt gut health and are associated with higher rates of depression, anxiety, and cognitive decline
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GLP-1 drugs like semaglutide are synthetic molecules designed to bind to and activate GLP-1 receptors directly, maintaining elevated GLP-1 activity for extended periods
Thus, observed potent induction of ferroptosis, GPX4-dependent novel suppression of mTOR pathway and DNA damage repair response in preclinical in vitro model of TC supports GPX4 targeting for therapeutic benefit in advanced therapy-resistant thyroid cancers
More serious but less common risks include pancreatitis, gallbladder disease, acute kidney injury (usually secondary to dehydration from gastrointestinal symptoms), and diabetic retinopathy complications, particularly in patients with pre-existing retinopathy who experience rapid improvement in blood glucose
