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Managing diarrhea Why it happens: While GLP-1 medications slow digestion overall, they can also cause the digestive system to become uncoordinated, sometimes leading to diarrhea

Food sits longer than the body expects

A few shed as much as 21% or even 22% of their body weight, depending on dose and compliance

When used for weight loss, semaglutide is available under the brand name Wegovy

Participants in the Phase 3 TRIUMPH-4 trial taking 12mg at 68 weeks lost an average of 28.7% of their body weight the most significant result reported at that stage for any obesity-related compound to date

This indicates that the desired and undesired effects of GLP-1 are indeed intertwined, said Yacawych