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One of the earliest biochemical changes seen in PD is a decrease in the levels of total GSH which occurs even before a reduction in mitochondrial complex 1 activity, dopamine levels, or the neurodegeneration that are all associated with the disease (Chinta et al., 2007)

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Possibly, the most relevant work regarding the regulation of sleep by DSIP has been conducted in the backdrop of insomnia

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[DOI] [PubMed] [Google Scholar] 66.Hansen J.G., Tang W., Hootman K.C., Brannon P.M., Houston D.K., Kritchevsky S.B., Harris T.B., Garcia M., Lohman K., Liu Y., et al