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To address this possibility, in a number of animal 118,119 and human studies, 120 high doses of anti-catabolic glucocorticoids, which inhibit the activation of MMPs 121 and the expression inflammatory cytokines, 122 have been administered

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European Journal of Clinical Nutrition, [online] 72(1), pp.105111.

Adsorptive-mediated transport at the BBB has also been exploited to target nanocarrier systems by using cationic lipids and cell penetrating peptides to increase binding and internalization at the brain capillary endothelium [29, 30], which has a highly negative surface charge [31]

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