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Resistance exercise significantly upregulates mRNA expressions of OPA-1, MFN2, FIS1, DRP1, MTFP1, and PINK1 and increases those of NRF1, OPA-1, FIS1, and Parkin proteins in skeletal muscle tissues, suggesting that resistance exercise promotes mitochondrial biogenesis, fission, fusion, and mitophagy and restores the levels of the marker proteins to their pre-intervention levels (Pileggi et al., 2023)

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Ann Rev Neurosci 13 : 2542

Knowing the fact that UF is hormone-dependent, which is mainly associated with the estrogen hormone ( Leiomyoma is a benign tumor with excessive ECM production

The breakdown of histamine is a multi-step process governed primarily by two enzymes: Diamine Oxidase (DAO), which degrades extracellular histamine in the gut, and Histamine N-methyltransferase (HNMT), which neutralizes intracellular histamine in the liver and central nervous system