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Some patients feel an energy boost within a few days, while others with severe neurological symptoms may take several weeks of treatment before noticing improvement

Insulin secretion was only affected by somatostatin at 12 mmol/l glucose, demonstrating that a tonic inhibition by endogenous somatostatin does not contribute to the very low levels of insulin at low glucose levels, whereas a paracrine inhibitory effect by local somatostatin plays a significant role in the regulation of insulin secretion at higher glucose levels

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1 , CD009461 (2013)

Nature 2006;444:643-6

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