Abbreviations DBS: Dried blood spot NGS: Next-generation sequencing OCTN2: Organic cation transporter 2 PCD: Primary carnitine deficiency PCR: Polymerase chain reaction References Cederbaum SD, Koo-McCoy S, Tein I, Hsu BY, Ganguly A, Vilain E, et al
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(Genome Medicine, 2012) used that dataset to identify GHK as inversely correlated with an emphysema-related lung destruction signature, then examined collagen remodelling in cultured lung fibroblasts
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Alterations in glycolytic pathways, fatty acid oxidation, and some amino acid metabolism in the high glucose state can affect mitochondrial oxidative phosphorylation processes