doi: 10.1002/adfm.202313540 23 QianJYLouCYChenYLMaLFHouWZhanZJ
Krebiehl G, Ruckerbauer S, Burbulla LF, Kieper N, Maurer B, Waak J, Wolburg H, Gizatullina Z, Gellerich FN, Woitalla D, Riess O, Kahle PJ, Proikas-Cezanne T, Krger R (2010) Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinsons disease-associated protein DJ-1
Topical application Topical delivery makes intuitive sense for a skin condition
Liu HY, Gu F, Zhu C, Yuan L, Zhu C, Zhu M, et al
In fact, during initiation, GSH counteracts ROS-induced DNA oxidation and DNA damage through a mechanism of elimination of carcinogens by the GSTs [26]
Interestingly, GSAAT(WT), GSAAT(C138S) and GSAAT(C396S) lines were still markedly redox responsive, and exhibited up to 20% higher enzyme activity when supplied with DTT relative to the UT control conditions, while the two gsa2 lines expressing GSAAT(C168S) and GSAAT(C190S) resulted only in 9% and 2% increased GSAAT activity upon addition of DTT to the extracts ( Supplementary Figure 3E )
