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Pellets were resuspended in DMEM/F-12 medium (Life Technologies, Carlsbad, CA, USA) supplemented with 20% foetal bovine serum (FBS, Pan Biotech, Aidenbach, Germany) and penicillin/streptomycin (Life Technologies) and plated on 10 cm cell-culture dishes

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Furthermore there is also some limited and inconsistent evidence that changes in transporter activity may contribute to the reductions in UA seen in PD and these are reviewed below

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