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Or, the glutamate can be further converted to GABA using the GAD1 enzyme, which requires the active form of vitamin B6 (P5P) as a cofactor.[ref] Genetic variants that reduce the conversion of B6 to its active form, P5P, could therefore impact GABA synthesis and GABAergic neurons

Gradual Decline Doesnt Have to Be the Norm Laura Mayeda, MD, MPH, a practicing nephrologist (kidney specialist) and a clinical assistant professor at the University of Washington in Seattle, views more healthy days as a sign that Ozempic helps maintain consistently higher well-being

1 shows the pathways and mechanisms of drugs used in MASLD

PMID 21548867