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Discovery of LX2761, a sodium-dependent glucose co-transporter 1 (SGLT1) inhibitor restricted to the intestinal lumen, for the treatment of diabetes

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Potential limitations of the study include: Small sample size: With only 52 participants, the study may not have been adequately powered to detect subtle effects

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The pharmacokinetic primary endpoint, AUC 0168h,sema,SS , was derived from the concentrationtime curve during a dosing interval (0168 h) at steady state using the linear trapezoidal method on the observed concentrations at actual time points

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