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Inflammation in the GI tract often leads to lower stomach acid which impairs the absorption of B12

Environmental pollutants, inadequate sleep, and oxidative stress may also affect skin clarity and tone over time

Environmental Toxins: Exposure to pollutants, heavy metals, and other toxins can deplete glutathione levels as the body uses it to detoxify

FIN56, an agonist of squalene synthase SQS, acts as a ferroptosis inducer, possibly due to the depletion of CoQ10 (Shimada et al., 2016)

They also tend to decrease appetite and slow digestion

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