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This timeframe allows providers to assess: Side effect severity Appetite changes Energy levels Overall tolerance If side effects are present but mild, staying at the starting dose longer often leads to improvement without sacrificing progress

This is a significant advantage over using sterile water, where the lack of a preservative means the solution should ideally be used within 24-48 hours to avoid the risk of bacterial growth

Semaglutide targets one receptor (GLP-1)

Recently, GLP-1 was highlighted as a regulator of diverse pathways, but its potential as the therapeutic target of depressive disorder was not described comprehensively

Sakata, K

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