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They can advise whether to continue with the pen or obtain a replacement

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This effect is most pronounced after the first dose and during the initial dose-escalation phase, and it tends to diminish over time

JAMA American Association of Clinical Endocrinology

Compared with tirzepatide, semaglutide 2.4 mg showed a significant 57% greater risk reduction for heart attack, stroke and cardiovascular-related death or death from any cause, in people with overweight or obesity and CVD, who did not have any gaps in their treatment lasting more than 30 days