Incretin-based therapies for the treatment of non-alcoholic fatty liver disease: a systematic review and meta-analysis
Results from the TRIUMPH-4 trial, published in December 2025, showed participants with obesity and knee osteoarthritis taking retatrutide 12mg lost an average of 28.7% of their body weight at 68 weeks
Theres also some initial data showing increased availability of free testosterone thanks to these drugs, as well as improved sperm quality, though data is mixed
If you use them as permission to not fix your sleep, stress, and basic nutrition, youre missing the point entirely
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Interestingly, compared with the model group, the TC and TG contents of the Lira group had a decreasing trend but the difference was not statistically significant