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Flohes objection points out that the rate constants for the spontaneous reactions of inter-conversion of thiol disulfides are negligibly small, with respect to those necessary to explain biological processes, and therefore the intervention of the enzymatic systems is of a crucial importance in determining the behavior of a biological system

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For more information, please refer to the individual studies cited in the manuscript

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During the same period, Chinas epilepsy prevalence and incidence reached 214.7 and 28.2 per 100,000, respectively, reflecting increases of 13.4 and 26.1% from 1990 levels

Maes M, Bonifacio KL, Morelli NR, Vargas HO, Moreira EG, St Stoyanov D, et al