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Approx 62-72% fat mass loss ( per Supplementary Appendix) vs

NaBPC157 is able to prevent vaginal atrophy in rats caused by castration

PMID 16820551

How much and when

Circulation 2018;138(12):1236-52

Mechanistically, nitric oxide synthase (NOS) converts arginine, NADPH, and oxygen into nitric oxide, which inhibits apoptosis by altering cellular redox states (50, 51)