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Acknowledgements The authors wish to acknowledge Humphrey Chukwudi Omeoga, of Thomas BegLey Laboratory, Department of Biological Sciences, State University of New York, at Albany, New York USA for using his licensed accessed BioRender for the diagrams sketching

Studies using HPLC data show significant increases in total thiol content after all kinds of metal exposure from different categories i.e

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doi:10.1186/1471-244X-4-25 [6] Caykoylu A, Kabadayi Sahin E, Ugurlu M

It is commonly investigated in preclinical research models relating to metabolic signalling pathways, cellular energy regulation, and enzymatic activity associated with nicotinamide N-methyltransferase (NNMT) interaction studies