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Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2/ mice

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Sun, F., Chai, S., Yu, K., Quan, X., Yang, Z., Wu, S., Zhang, Y., Ji, L., Wang, J., & Shi, L

Limitations A key limitation was the rarity of trials directly comparing tirzepatide and semaglutide, leading to indirect comparisons

Compounded products are not FDA-approved and have not been evaluated by the FDA for safety or efficacy