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They play a role in: Increasing insulin secretion: helping reduce blood glucose levels in individuals with impaired insulin sensitivity

Another cluster of hydrogen bonding and ionic bonds are formed between the Exendin-4 amino acids Glu24 and Lys27, interacting with the GLP-1R Glu127

Western blotting analysis L6 myotubes were lysed, sonicated, and homogenized in radioimmunoprecipitation assay (RIPA) lysis buffer, supplemented with protease and phosphatase inhibitors

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