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Sildenafil is absolutely contraindicated with nitrate medicines (such as glyceryl trinitrate for angina), and men with unstable angina, recent serious cardiovascular events, or uncontrolled hypertension should be referred to cardiology for specialist review before treatment
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People who drink alcohol regularly or heavily should speak to a doctor before using paracetamol, as regular alcohol use increases the risk of liver injury from paracetamol even at doses within the recommended limit
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