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Most titration schedules begin low, commonly at 2.5 mg weekly, precisely to let the body acclimate before the dose rises, and the typical pattern is that nausea is most noticeable in the 24 to 72 hours after an injection, particularly the first injection at a new dose, then eases over the following days as the week goes on

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An automated high-throughput fluorescence in situ hybridization (FISH) assay platform for use in the identification and optimization of siRNA-based therapeutics

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