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Mutually exclusive HCRU endpoints included inpatient hospitalizations, emergency room (ER) visits, and outpatient medical services (including physician office visits, and other outpatient services)

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In the transgenic AD mouse model Tg2576, marked by mutant APP overexpression in the brain, melatonin treatment exhibited a trend of elevated A levels in cervical and axillary lymph nodes, concomitant with a decreasing trend in brain A [76]