Copper has a complex role in oxidative biology participating in both prooxidant chemistry (where free or weakly bound copper can catalyze damaging reactive-oxygen-species generation) and antioxidant chemistry (as the cofactor of Cu/Zn superoxide dismutase)
Mitochondria may be active, but without enough antioxidant support to balance everyday oxidative exposure
Hypokalemia and sudden death may occur in severe megaloblastic anemia which is treated intensely
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Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism
WARNINGS: Not recommended for people under age 18. Not recommended in case of kidney, heart and cardiovascular disease, neither for people who suffer from diseases accompanied with seizures