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However, the amount of glucose lost in the urine should result in a greater weight loss than is typically observed and a compensatory increase in food intake blunts the weight loss (142)

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Compounded semaglutide is used when the patient cannot use the brand-name medication, when the patient is allergic to certain ingredients of the brand-name medication or the patient needs a customized version free of that allergen, or when there is a need for personalized dosing

Bottom line: Both have real clinical evidence, which is unusual for peptide stacks

However, because GLP-1s slow gastric emptying, they can affect absorption of some oral medications

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