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Among 13 identified lipid metabolites, 11-Dehydro thromboxane B2, 2-Methoxyestrone, 7-Hydroxytestosterone, Ergosterol, geranyl pp, and PC 36:1 were involved in pathways such as Arachidonic acid metabolism, Serotonergic synapse, Steroid hormone biosynthesis, Glycerophospholipid metabolism, Linoleic acid and -Linolenic acid metabolism (Figure 6E)

However, to facilitate coordination of Medicare and Medicaid services, the Medicare Improvements for Patients and Providers Act (MIPPA) of 2008--as amended by the Patient Protection and Affordable Care Act--required all DSNPs to have contracts with the states in which they operate (CMS, 2016b)

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Nature 588 , 327330 (2020)

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