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Take at the same day each week, any time of day, with or without food

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Note that upper arm injections typically require administration by a caregiver or trained person

Ask a close friend, companion, spouse, or relative to learn how to administer vitamin B12 shots, or at least hold a mirror for you while you give yourself the injection, and rub out the pain afterwards to prevent bruising and other painful side effects

Keeping an open channel of communication ensures the safe application of any medicine.

[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Lan G., Ni K., Lin W