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Knockout of one allele of QPRT recapitulates these effects and increases susceptibility to AKI compared with control mice, which could be prevented by augmenting NAD + metabolism with oral NAM supplementation

PubMed PMID: 32690803

In addressing motor dysfunction induced by METH, transcranial magnetic stimulation has shown potential for restoring motor control by modulating cortical excitability ( Additionally, physical exercise has been recognized as an effective adjunctive intervention for mitigating the cognitive and motor impairments associated with chronic METH use

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2 Mitochondrial structure Mitochondria are double-membrane-bound organelles

Gastroenterology 149 , 13921398 (2015)