A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility
Barragn JM, Rodrguez RE, Blzquez E
PlexusDx also offers combination therapiessuch as GLP-Squared Injection, which pairs semaglutide with tirzepatidefor patients whose genetic profile suggests dual GLP-1 and GIP pathway engagement may yield superior outcomes
For now, the best path forward is to stick with therapies backed by solid, long-term data, using GLP-1 agonists as a potential supplement for managing metabolic issues
NICE Technology Appraisal 875 (Wegovy) and TA664 (Saxenda) recommend these treatments within specialist tier 3 or 4 weight management services for adults with a BMI of 35 kg/m or above (or 32.5 kg/m or above for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds), with weight-related comorbidities
Kraegen, E.W