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(13) applied multiple techniques, including region-specific injections of GLP-1R antagonists, lesioning specific nerves and nuclei, ex vivo electrophysiological studies, and peripheral administration of a fluorescently labeled liraglutide molecule in rats, WT mice, and Glp1r / mice to dissect mechanisms that link peripheral administration of a GLP-1R agonist to reduced food intake and weight loss

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*Correspondence: Juan Du, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Research protocols typically use 0.52mg per administration, with most appetite studies employing 1mg daily or every 48 hours