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Acute toxicity data from rodent models puts the LD50 well above concentration ranges used in published research protocols

Manigrasso, J

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Seminars in hematology

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Its Phase 3 weight-loss figures (in the low-to-mid 20% range) and its late-2025 FDA filing belong to the combination product, not to standalone cagrilintide, which remains at the Phase 2 stage with a peer-reviewed monotherapy result of about 10.8% at 26 weeks