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Patients should also be aware of potential hair loss , which affects some GLP-1 users due to rapid weight loss and caloric restriction rather than the medication itself

Abdominal fat loss, as well as sustained reductions of fasting insulin levels and markers of IR, have been also shown to individuals with overweight/obesity, prediabetes, PCOS and OSA during their administration [31, 38, 6770]

Starting at the lowest dose and gradually increasing it helps manage common gastrointestinal side effects like nausea or vomiting

A registered dietitian can help you establish an appropriate caloric target that supports weight management without compromising nutritional adequacy

Others have a step therapy process in place, in which cheaper weight loss medications have to be tried first before theyll cover GLP-1 medications, says Brown

Current formulations of GLP-1 analogs rely primarily on subcutaneous injections, which may pose challenges to patient convenience and long-term adherence