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Cardioprotective glucose-lowering agents and dementia risk: a systematic review and meta-analysis

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These effects also appear to have a broader influence on metabolic health, potentially mediated through the gut microbiome

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Relevant studies have found that exendin-4 could mediate the neuroprotective effect on -aminobutyric acid neurons in the piriform cortex and striatum and play a neuroprotective role in a cAMP/PKA- and PI3K/AKT-dependent manner after stroke (84, 85)