Sydow K, Daiber A, Oelze M, Chen Z, August M, Wendt M, Ullrich V, Mulsch A, Schulz E, Keaney Jr JF, Stamler JS, Munzel T
Khanfar A, Al Qaroot B
Ice crystal formation during freezing physically damages the peptide structure in solution
The use of these proteins would be based on their expected biological activity: DSIP as the active peptide expected to induce sleep, and CBBBP to facilitate entry into brain
The specific binding of glutathione to the GST-tag results in high purity and high yield in a single step purification process
A prevalent idea is that opioid tolerance is a complex, multifaceted process that likely involves the interplay of multiple regulatory mechanisms occurring both at the level of individual opioid-responsive cells and at the level of neural circuits