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10.1016/j.pnpbp.2020.110228 57 SestarioC

SURMOUNT-2 included adults with a BMI of 27 kg/m 2 or higher, diabetes and HbA1c of 7% to 10% on a stable diabetes therapy who were randomly assigned to once-weekly tirzepatide 10 mg, tirzepatide 15 mg or placebo for 72 weeks

In some repair models, new vessel formation may support a tissue-model repair hypothesis, but angiogenesis is also relevant in pathological contexts

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