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Exendin-4 is a 39 amino acid peptide with 53% identity to GLP-1 (34) and is fully active at GLP-1 receptors and not degraded by DPP-4

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The recent identification of hybrid ketoacid dehydrogenase complexes between the E1 subunit of OADHc (DHTKD1) and the OGDHc 40 indicates that more complex crosstalk exists between ketoacid dehydrogenases, and we speculate that these hybrid complexes may be more susceptible to acyl-lipoyl adduct formation