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Concomitantly, GLP-1RAs suppress the expression of lipogenic transcription factors and enzymes, including sterol regulatory element-binding protein 1c (SREBP-1c) and fatty acid synthase (FAS), resulting in reduced de novo lipogenesis

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Track Body Composition, Not Just Weight If you are on a GLP-1 medication, I strongly recommend tracking body composition rather than relying solely on the scale

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Human thyroid C-cells have very few GLP-1 receptors, and large clinical trials have not shown an increased risk compared to placebo