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Larger and longer-term clinical trials are needed, and supplementation with other compounds important for methionine metabolism, such as vitamin B6, should be considered in ALD patients

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Intergenic miRNAs are transcribed by their own promoters while intronic miRNAs depend on the promoter of their host gene

Moreover, GST isozymes (Alpha, Mu, and Pi) are frequently over-expressed in neoplastic tissues and have been considered as an important marker for a number of tumors such as lung, ovarian, breast, and gastric carcinoma [2, 3]

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