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For peripheral vascular disease, where reduced blood flow to the extremities causes pain and tissue damage, this collateral activation mechanism could theoretically provide meaningful benefit
If youre genuinely deficient or have an absorption issue which is common with vegetarians, older adults, GI conditions, and people on metformin or PPIs yes, B12 injections often produce meaningful improvements in energy, mental clarity, and mood within days to weeks
Weeks 17-20: 12.5mg (1.25mL or 125 units)
Signals endometrial receptivity for implantation
How Vitamin B12 injections work, their advantages over oral supplements, and who can benefit most from this treatment option