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For this reason, patients who have had, or have family members who have ever had medullary thyroid carcinoma should not use liraglutide, nor should those who have an endocrine system condition called multiple endocrine neoplasia syndrome type 2

So, higher GLP-1 means the brain wants less food

Switching GLP-1 Medications If semaglutide is not providing the results you want, a provider might suggest switching to a different GLP-1 receptor agonist, such as tirzepatide (the active ingredient in Mounjaro and Zepbound)

Effects on Hypertension Hypertension poses an increasingly serious public health problem worldwide

Int J Endocrinol 2020:1484321

Some people may experience mild to serious side effects during treatment with Janumet or Janumet XR