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Ethics approval and consent to participate All animal experiments were undertaken in accordance with the National Institute of Health Guide for the Care and Use of Laboratory Animals, with the approval of the Ethics Committee of the Second Affiliated Hospital, Zhejiang University School of Medicine (Permit number: 2024-260)

Perhaps most striking is the scope of its influence at the gene expression level

Abstract Autism spectrum disorder (ASD) affects about 1 in 45 individuals in the United States, yet effective treatments are yet to be defined

Post probiotics include enzymes, short-chain fatty acids, secreted proteins, organic acids, vitamins, biosurfactants, neurotransmitters, bacteriocins, cell free supernatants, and peptides [20, 24]

Next day, invert the vial several times or gently pipette the solution up and down before use

These effects make sense given MOTS-cs known ability to increase nitric oxide bioavailability (through AMPK) and reduce inflammation, both of which are critical for healthy blood vessels