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No effect was seen by Koehler et al (58) and in the work of Tatarkiewciz et al (108) high doses of exenatide inhibited the pancreatitis

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10.1016/j.metabol.2016.02.002 39 FarrO

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Results Disruption of the glucagon receptor significantly alters both gene expression and the interactive network of cells To comprehensively examine the functional and physiological changes in cells following GCGR blockade, we conducted single-cell RNA sequencing (scRNA-seq) on islets isolated from 1214-week-old male wild-type (WT) and GCGR-knockout (KO) mice (Fig