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N Engl J Med (1991) 325:599605.10.1056/NEJM199108293250902 70 HansenPSBrixTHIachineIKyvikKOHegedusL
[12] Fortunately, no congenital abnormalities in humans have been directly linked to biotin deficiency, and ensuring an adequate intake (through diet or a prenatal vitamin) appears to maintain normal pregnancy outcomes
Furthermore, phase II studies were undertaken to prove the efficacy of mecasermin rinfabate (IGF-1/IGFBP-3) in paediatric severe burns and had promising outcomes when doses of 14 mg/kg/day [269273] were used
6 In SELECT, this small increase didnt translate into more cardiac events
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