In a healthy gut, these massive endotoxin molecules are safely contained within the intestines and excreted
It is a semiterpene lactone with antimalarial effect
Most studies are small-scale, lack robust methodology, or have not been replicated in larger populations
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However, very limited information is available about the exact metabolic functions of disease-induced GST isoenzymes and about their endogenous substrates
Additionally, there were very few clinically associated studies, where many of the articles available consisted of literature and narrative reviews or non-evidence-based guidelines based on literature searches with limited methods reported