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Pcsk5 ECKO mice and Pcsk5 WT littermate controls showed no significant differences in cardiac function, myocardial capillary, and arteriole density, or plasma levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) (Fig

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In the second step, the resolving cysteine of one Prx subunit attacks the peroxidatic cysteine-sulfenic acid of the other subunit generating an inter-subunit disulfide bond [46, 75]