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(Source: National Institutes of Health, Office of Dietary Supplements)

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There are already frameworks to support this, such as NICE [National Institute for Health and Care Excellence] guidance for pain management and prescribing e.g., NG193 and NG215. Davies added that pharmacists should support patients and prescribers to better understand these risks and help to challenge the perception that gabapentinoids are low-risk options. In January 2026, the Medicines and Healthcare products Regulatory Agency announced warnings on the risk of dependency and addiction for gabapentinoids, benzodiazepines and z-drugs are to be strengthened, following a safety review by the regulator

Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH

The study found significant improvements in sleep quality, including reduced sleep latency, higher sleep efficiency, and less daytime sleepiness