For people with type 2 diabetes, the STEP-2 trial showed average weight loss of around 9.6% on the 2.4mg dose, roughly 64% of the result in people without diabetes 4
Sometimes it delivers nothing at all
Following the ingestion of D-allulose, body fat percentage and body fat mass significantly declined.* Compared to the sucralose group, the group given the higher dose of D-allulose had a significant decrease in not only body mass index, but also total abdominal and subcutaneous fat areas, as measured by CT scans.* The FDA considers D-allulose to be GRAS (generally recognized as safe) with an intake of less than 0.5 to 0.6 g per kg of body weight per day
To avoid medication errors between SEMGLEE and other insulins, instruct patients to always check the insulin label before each injection [see ADVERSE REACTIONS ]
Dosage may be adjusted in increments of 10 mg or 20 mg at approximately weekly intervals up to maximum recommended dosage of 70 mg once daily [see Clinical Studies (14.1)]
This structured approach allows supplements and lifestyle changes to work more effectively over time
