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No tolerance developed to this protective effect, which appeared to be mediated by (1) the activation of 5-HT 1A receptors, as it was antagonized by the administration of WAY100635 30 min before stress exposure

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The study 15 on cocaine use disorder only observed the effect of acute treatment with exenatide in a small set of patients, and thus more evidence is needed to understand the role of GLP-1 analogs in cocaine use disorder

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PlexusDx recommends keeping a symptom log during your first 46 weeks to distinguish between the two